Assoc. Prof.
Department of Chemical Engineering, Boğaziçi University, Bebek 34342, Istanbul-TURKEY
+90 (212) 359 7471

PhD: Biochemistry and Molecular Biology, Purdue University, USA, 2006
MS: Chemical Engineering, Boğaziçi University, Turkey, 1998
BS: Chemical Engineering, Boğaziçi University, Turkey, 1996

Honors and Awards: 

- Purdue Research Fellowship

Research Interests: 
  • Protein Structure
  • Function and Interactions
  • Computational biology systems biology
Selected Papers: 
  • 1. Ozcan A, Olmez EO, Alakent B. Effects of Protonation State of Asp181 and position of active site water molecules on the conformation of PTP1B. Proteins. 2012 Dec 12. doi: 10.1002/prot.24234. [Epub ahead of print] PubMed PMID: 23239271.
  • 2. Olmez EO, Alakent B. Alpha7 helix plays an important role in the conformational stability of PTP1B. J Biomol Struct Dyn. 2011 Apr;28(5):675-93. PubMed PMID: 21294582.
  • 3. Huang H, Ozkirimli E, Post CB. A Comparison of Three Perturbation Molecular Dynamics Methods for Modeling Conformational Transitions. J Chem Theory Comput. 2009 Apr 9;5(5):1301-1314. PubMed PMID: 20161143; PubMed Central PMCID: PMC2731424.
  • 4. Ozkirimli E, Yadav SS, Miller WT, Post CB. An electrostatic network and long-range regulation of Src kinases. Protein Sci. 2008 Nov;17(11):1871-80. doi: 10.1110/ps.037457.108. Epub 2008 Aug 7. PubMed PMID: 18687871; PubMed Central PMCID: PMC2578809.
  • 5. Oh H, Ozkirimli E, Shah K, Harrison ML, Geahlen RL. Generation of an analog-sensitive Syk tyrosine kinase for the study of signaling dynamics from the B cell antigen receptor. J Biol Chem. 2007 Nov 16;282(46):33760-8. Epub 2007 Oct 3. PubMed PMID: 17913708.
  • 6. Ozkirimli E, Post CB. Src kinase activation: A switched electrostatic network. Protein Sci. 2006 May;15(5):1051-62. Epub 2006 Apr 5. PubMed PMID: 16597828; PubMed Central PMCID: PMC2242506.